Microarray analysis revealed clinically significant, segmental aneuploidies not detected about karyotyping . On microarray, 1399 samples were identified as having copy-number variants; of the, 1234 were classified as common benign, including 26 in which the fetus was a carrier . Thirty-five copy-quantity variants, happening in 35 of the 3822 fetuses , were on the predetermined set of pathogenic copy-quantity variants. Of the rest of the 130 samples, 36 were considered likely to be benign by the study’s clinical geneticist, and 94 maintained a classification of uncertain significance and were adjudicated by the Clinical Advisory Committee.Glotzer et al. Also reported a romantic relationship between device-detected atrial tachycardia and embolic events.17 However, that research also included patients with previously documented atrial fibrillation and did not show a significant association in the predefined major analysis. The prevalence of subclinical atrial tachyarrhythmias may be higher in patients with pacemakers than in other high-risk patient groups. Sinus-node dysfunction is associated with an increased risk of atrial fibrillation.20,21 Furthermore, patients with atrioventricular-node disease may be much more likely to be asymptomatic when atrial tachyarrhythmias occur, due to reduced atrioventricular conduction.