However, the unavailability of a therapeutic intervention of proven efficacy regarding documented maternal illness has been considered to be a significant obstacle to the execution of routine serologic screening of women that are pregnant. In 2005, a nonrandomized study showed that whenever CMV-specific hyperimmune globulin was administered to pregnant women with primary infection, the rate of mother-to-fetus transmission significantly decreased, from 40 percent to 16 percent , and the chance of congenital disease decreased significantly, from 50 percent to 3 percent .5 Other nonrandomized studies have shown a decrease in the number of congenitally infected infants born to mothers who was simply treated with hyperimmune globulin or improved outcomes in CMV-infected infants.6-9 We designed the current randomized, controlled scientific trial to confirm the reported efficacy of CMV-specific hyperimmune globulin in preventing fetal infection previously.10 Methods Research Oversight The Congenital HCMV Infection Avoidance trial was a phase 2, double-blind, placebo-controlled, parallel-group trial.Chronic cystitis can be a recurrent bladder infection. The primary symptoms of chronic cystitis are chronic discomfort when peeing and a continuous urge to visit the bathroom. If we realize about any of it and do following things inside our daily life, we are able to keep ourselves from it at a great degree. When urinate, remove all the urine and do not leave any in the bladder. Besides, after having sex, make an effort to urinate for just one time. Change underwear frequently and wash it meticulously and place it sunshine so that the bacteria could be killed by sunshine. Hygiene is normally the most important and the last thing to end up being ignored.