Zabaneh, M.D., Sandra Tong-Starksen, M.D., Martha R. Mayo, Pharm.D., Hong Tang, M.S., Krishna R. Polu, M.D., Anne-Marie Duliege, M.D., and Steven Fishbane, M.D. For the PEARL Study Groups: Peginesatide for Anemia in Sufferers with Chronic Kidney Disease Not Receiving Dialysis The 1989 approval of recombinant human erythropoietin facilitated sustained correction of anemia in chronic kidney disease and freed many individuals undergoing dialysis from reliance on transfusions.1,2 Increases in hemoglobin levels from approximately 6 to 7 g per deciliter to approximately 11 to 12 g per deciliter improved symptoms, quality of life, and physical capacity.3,4 Subsequent molecular modifications generated two erythropoiesis-stimulating agents with longer in vivo half-lives , offering the potential of much less frequent administration.5-7 Both are based on the endogenous erythropoietin molecule.8 Peginesatide , a peptide-based ESA,9,10 was approved in the usa in March 2012 for the treatment of anemia due to chronic kidney disease in adults who also are undergoing dialysis.He posted twitpics of himself obtaining thinner and slimmer regularly. And did you know that Renee Zellweger gained almost 30 pounds to perform the title role in ‘Bridget Jones’s Diary.’ And there’s Christian Bale, who lost 63 pounds to play the business lead in ‘The Machinist.’ See 10 most shocking celebrity weight changes.
Affymetrix reports net lack of $17.9 million for third quarter 2012 Affymetrix, Inc., today reported its operating results for the third quarter of 2012. Total income for the one fourth was $79.6 million, including approximately $17.6 million in revenue from eBioscience during the third quarter of 2012.